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Cisco Secure Access Help Network Requirements for Secure Access Secure Access SaaS Tenants Microsoft 365

Last updated: Aug 07, 2025

Microsoft 365

Microsoft 365 traffic is sent directly to the Secure Access secure web gateway (SWG) for these deployment methods:

  • VPN and Network Tunnels established on a network device
  • Cisco Secure Client with the VPN and Umbrella Roaming Security modules
  • Secure Access PAC file

To stop network traffic from connecting to the Secure Access SWG, add External Domain entries manually or route the traffic direct to the internet from your connecting devices.

If your organization's firewall rules prevent any third-party applications, allow the following IP addresses:

  • 52.73.52.135
  • 52.71.142.118
  • 52.40.204.69
  • 52.35.119.173
  • 52.27.150.153